29 SBIR-participating federal agencies targeted.
Every major federal AI buyer — from DoD and the intelligence community to HHS, NASA, NSF, and the civilian departments — has a dedicated landing page covering the mission, programs, vehicles, and how Precision Federal plugs in.
Department of Defense and components
DoD-wide, individual services, rapid-acquisition components, and AI-focused organizations.

Department of Defense
DoD-wide SBIR/STTR across all components.
U.S. Army
xTech, AI2C, AFC, ARCYBER, CECOM, TRADOC.
U.S. Navy
NavalX, NRL, fleet logistics, predictive maintenance.
U.S. Air Force
AFWERX, AFRL, Open Topic SBIR, ISR AI.
U.S. Space Force
SpaceWERX, STRATFI/TACFI, Orbital Prime, SSC, SDA.
DARPA
AI Next, I2O, DSO, MTO. GARD, ACE, SCORE.
Defense Innovation Unit
CSO, prototype OTs, 60–90 day awards, AI Portfolio.
SOCOM
SOFWERX, SOF AT&L, Concept Challenges, MFP-11.
CDAO
Task Force Lima, Maven Smart System, TradeWind, AI RCC.
DTRA
Defense Threat Reduction Agency. Counter-WMD AI/ML, CBRN modeling, threat anticipation.
Chem-Bio Defense
DoD CBDP via JPEO-CBRND. Biosurveillance, sensor fusion, medical countermeasure ML.
OSD / SCO
Strategic Capabilities Office. Rapid integration of existing systems, 3–5 year fielding.HHS and sub-agencies
HHS and its SBIR-participating sub-agencies — NIH runs the largest federal biomedical SBIR program and CDC, CMS, and FDA each publish AI and data topics regularly.

Health and Human Services
Parent department. Runs the largest federal SBIR program by dollar volume, primarily through NIH.
NIH
27 institutes, eRA Commons, biomedical AI, genomics.
CDC
Disease surveillance AI, public health data platforms.
CMS
Medicare, fraud detection ML, claims data platforms.FDA
Drug safety AI, SaMD compliance, trial data NLP.DHS and cybersecurity components
Homeland security organizations buying AI, data fusion, and cyber tooling — an SBIR-participating agency with a dedicated small business research program.
NSF, DOE, NASA, NOAA, USDA, NIST
Science and research-focused agencies with strong SBIR programs and open AI/ML topics.

NSF
SBIR Project Pitch, Research.gov, AI/ML topics.
DOE
National labs, grid AI, scientific ML, HPC.
NASA
JPL, Ames, Goddard, space autonomy, earth observation.
NOAA
Climate ML, ocean data, weather modeling.
USDA
Agricultural AI, precision ag, food safety, rural broadband.
NIST
AI safety, measurement science, post-quantum crypto.DOT, Education, EPA, Commerce
Civilian federal departments running their own SBIR programs — each publishes AI and data topics every cycle.

DOT
Transportation AI, autonomous systems, infrastructure.
Education
Adaptive learning AI, educational assessment, accessibility.
EPA
Environmental ML, emissions monitoring, chemical safety AI.
Commerce
Census, USPTO, ITA, BIS, export controls AI.Targeting an agency not listed?
Precision Federal is registered on SAM.gov, DSIP, NSF Research.gov, and SBA's SBIR Company Registry — we can compete at any federal agency. Ask.

